Objetivo: describir los hallazgos de imagen clave en los estudios de RM estructural de las demen- cias de origen neurodegenerativo más frecuentes: enfermedad de Alzheimer, demencia vascular, demencia de cuerpos de Lewy, variantes de la demencia frontotemporal, parálisis supranu- clear progresiva, variantes de la atrofia multisistémica, parkinson-demencia y degeneración corticobasal.
Conclusión: El papel de la resonancia magnética hoy en día ya no está limitado a excluir causas subyacentes de deterioro cognitivo, sino que puede mostrar patrones de atrofia y otros datos con un alto valor predictivo para determinadas demencias que, aunque no son específicos ni únicos de cada patología, pueden ayudar a confirmar una sospecha diagnóstica o a identificar inicios tempranos de determinados procesos. Por ello es importante que los radiólogos conozcan los hallazgos típicos de las demencias más frecuentes.

Palabras clave: Resonancia magnética; Atrofia; Demencia; Enfermedad de Alzheimer; Parálisis supranuclear progresiva; Demencia vascular; Atrofia multisistémica; Enfermedad de Parkinson; Demencia frontotemporal

Background: Breast cancer is a leading cause of death worldwide, and despite consistent observation that cancer incidence increases with advancing age, there still remains a gap in the adequate characterization of this disease in elderly women.
Purpose: Characterization of the clinical, imaging and histological features of breast cancer in women aged 80 years or older and comparison with features from a representative group of younger women.
Methods: Single-center retrospective analysis of clinical, imaging and histopathological findings of women aged 80 years or older submitted to magnetic resonance imaging and comparison with a representative population of women under 80.
Results: Older patients have more advanced disease at presentation, with a significant difference in the clinical stage distribution between the two groups (P-Value = 0.004). Younger patients have a higher prevalence of ductal carcinoma in situ (P-Value = 0.02), with more extensive DCIS disease (P-Value = 0.025). DCIS in patients of 80 years or older is more frequently associated with positive estrogen receptors (P-Value = 0.03). Moderate agreement was found in the concordance between the clinical stage according to breast MR imaging and the pathological stage in patients of 80 years or over (Kappa = 0.50) and in younger aged patients’ group (Kappa = 0.55). Conclusion: Breast cancer in elderly women presents different characteristics from those in younger aged patients.

Keywords: Breast neoplasms; Carcinoma intraductal noninfiltrating; Carcinoma ductal; Magnetic resonance imaging.